Medical Weight Loss in Wilmington, NC
Personalized, nurse-led weight loss support designed around your health, lifestyle, and goals, including evaluation for GLP-1 and other prescription weight management options when appropriate.
A More Personalized Approach to Weight Loss
Weight management is not one-size-fits-all. Your health history, medications, habits, lifestyle, and goals all play a role in determining which approach may be right for you.
At In-Depth Health & Performance, Nurse Practitioner Megan Monroe provides one-on-one consultations and personalized guidance for adults interested in medically supported weight loss. When clinically appropriate, prescription options may be considered as part of a broader plan.
Prescription weight-management medications can help some eligible patients, but they are not appropriate for everyone and work best alongside sustainable nutrition, activity, sleep, and behavioral habits.
Medical Weight Loss Options
SEMAGLUTIDE
Seamglutide is a peptide that mimics the action of (GLP-1), a hormone that plays a critical role in regulating blood sugar levels and appetite. Initially developed as a medication for type 2 diabetes, Semaglutide has gained popularity for its effectiveness in weight loss and obesity management.
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Significant Weight Loss: One of the most sought-after benefits of Semaglutide is its ability to promote weight loss. The weight loss effect is primarily driven by Semaglutide’s ability to suppress appetite, reduce caloric intake, and promote feelings of fullness, making it easier for individuals to adhere to a reduced-calorie diet.
Reduced Appetite: Semaglutide effectively suppresses appetite by acting on the central nervous system. This leads to a reduction in food cravings and helps individuals eat less without feeling deprived. For people struggling with overeating or emotional eating, this can be a highly beneficial effect.
RETATRUTIDE
Retatrutide is a triple agonist peptide that functions as a potent metabolic regulator by mimicking three different natural hormones. It belongs to the next generation of weight loss and metabolic therapies that simultaneously stimulate the GLP-1, GIP, and glucagon receptors. This "triple-threat" approach is designed to suppress appetite, optimize insulin secretion, and actively increase the body's energy expenditure and fat burning.retatrutide has demonstrated the ability to produce weight loss exceeding 24% of total body weight, while also significantly reducing liver fat and improving blood sugar levels. Because it targets the glucagon receptor specifically, it offers a more comprehensive approach to body composition and metabolic health than standard dual-agonist peptides.
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Exceptional Weight Reduction: Participants on the highest dose achieved an average weight loss of 24.2% at 48 weeks. Phase 3 suggests even higher potential, reaching up to 28.7% over 68 weeks.
Reversal of Fatty Liver Disease: Perhaps its most unique benefit is the dramatic reduction in liver fat. In a substudy of patients with obesity and NAFLD/MASLD, 90% achieved normal liver fat levels (less than 5%) after 48 weeks on high doses.
Improved Glycemic Control: Retatrutide significantly lowers HbA1c levels. In clinical studies, 72% of participants with prediabetes returned to normal blood sugar levels after 48 weeks of treatment.
TIRZEPATIDE
Tirzepatide is a peptide developed for the treatment of type 2 diabetes and obesity. It is a dual GLP-1 and GIP receptor agonist, meaning it mimics the effects of two hormones in the body: glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP). Both hormones play important roles in regulating blood sugar, insulin secretion, satiety, and fat metabolism.
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Significant Weight Loss: One of the most notable benefits of Tirzepatide is its ability to promote weight loss. Clinical trials have shown that individuals taking Tirzepatide for weight management experienced substantial reductions in body weight, with many individuals losing 10% or more of their body weight. This weight loss is primarily driven by reduced appetite, increased satiety, and enhanced fat metabolism.
MOTS-C
MOTS-C is a peptide that works by Sensing cellular stress and energy deficiency, working to ensure significant energy level changes as well as shifting the metabolism toward glucose uptake, fat burning, and mitochondrial efficiency.
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Improved Insulin Sensitivity
Enhanced Fat Metabolism
Boosted Exercise Capacity
NURSE-LED EVALUATION
Meet one-on-one with Megan to review your health history, goals, medications, and weight loss concerns.
PERSONALIZED TREATMENT OPTIONS
Explore an individualized plan that may include prescription weight management medication when medically appropriate.
BUILT AROUND REAL LIFE
Create a realistic approach that considers your schedule, lifestyle, preferences, and long-term goals.
ONGOING GUIDANCE
Receive continued support, progress monitoring, and adjustments based on how your plan is working for you.
Your first visit includes a private conversation with Megan about your medical history, previous weight loss efforts, current medications, lifestyle, and goals.
She will review whether medically supported weight loss may be appropriate, explain available options, discuss possible benefits and risks, and answer your questions. If treatment is recommended, you will receive clear guidance on next steps and follow-up care.
What to Expect During Your Consultation
Medical Weight Loss FAQs
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Megan will review your medical history, current medications, previous weight loss efforts, lifestyle, concerns, and goals before discussing possible next steps.
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GLP-1 and other prescription weight management options may be discussed when medically appropriate. A consultation is required to determine eligibility and treatment recommendations.
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No. Prescription weight loss medications are not right for everyone. Eligibility depends on factors such as your health history, current medications, weight-related risks, and provider evaluation.
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No. Prescription treatment is generally used alongside sustainable habits involving nutrition, movement, sleep, and overall wellness.
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Results vary widely. Your response depends on your treatment plan, health, habits, medication tolerance, and other individual factors. No specific amount or timeline can be guaranteed.
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Yes. Follow-up care allows Megan to monitor progress, discuss side effects or concerns, and determine whether your plan should be continued or adjusted.ption
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No. The FDA warns that unapproved compounded GLP-1 products do not undergo the same review for safety, effectiveness, or quality as FDA-approved medications. The exact products offered by In Depth should be stated accurately and reviewed with Megan before this FAQ is published.
Start With a Conversation
Schedule a private medical weight loss consultation with Nurse Practitioner Megan Monroe at In-Depth Health & Performance in Wilmington, NC.
Visit Us
5424 Oleander Drive, Suite 10
Wilmington, NC 28403
Hours
Tuesday–Saturday 10am–7pm
Monday 12pm–7pm
Phone
(910) 769-1589